Tirzepatide is a glucagon-like peptide-1 (GLP-1) receptor agonist that also acts on the gastric inhibitory peptide (GIP) receptor, leading to improved glycemic control, weight loss, and reduction in cardiovascular risk factors. Tirzepatide has been shown to significantly reduce HbA1c levels (a measure of average blood sugar control over several months) compared to placebo and other diabetes medications. Tirzepatide also leads to significant weight loss, with some patients losing up to 15% of their body weight. Tirzepatide has also been shown to reduce cardiovascular risk factors such as blood pressure and cholesterol levels.GLP-1 medications act on the brain to modulate your appetite and reduce hunger, which can help you lose weight. GLP-1 medications also bind to receptors on stomach cells, slowing stomach emptying, which makes you feel full longer. Blood sugar lowering effects without any increase in hypoglycemia. This medication reduces body weight, lipids, blood pressure, inflammatory markers, oxidative stress, and endothelial dysfunction. Tirzepatide can be combined with a low-carb/low-calorie dietary plan. The once-weekly dosing regimen may improve patient adherence to treatment compared to daily or multiple-daily injections.

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